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Glycosylated SV2 and Gangliosides as Dual Receptors for Botulinum Neurotoxin Serotype F
Botulinum neurotoxin causes rapid flaccid paralysis through inhibition of acetylcholine release at the neuromuscular junction. The seven BoNT serotypes (A-G) have been proposed to bind motor neurons via ganglioside- protein dual receptors. To date, the structure-function properties of BoNT/F host re...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709598/ https://ncbi.nlm.nih.gov/pubmed/19476346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9002138 |
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