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Glycosylated SV2 and Gangliosides as Dual Receptors for Botulinum Neurotoxin Serotype F

Botulinum neurotoxin causes rapid flaccid paralysis through inhibition of acetylcholine release at the neuromuscular junction. The seven BoNT serotypes (A-G) have been proposed to bind motor neurons via ganglioside- protein dual receptors. To date, the structure-function properties of BoNT/F host re...

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Bibliografiske detaljer
Main Authors: Fu, Zhuji, Chen, Chen, Barbieri, Joseph T., Kim, Jung-Ja P., Baldwin, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709598/
https://ncbi.nlm.nih.gov/pubmed/19476346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9002138
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