Cholesterol- and Sphingolipid-rich Microdomains Are Essential for Microtubule-based Membrane Protrusions Induced by Clostridium difficile Transferase (CDT)

Clostridium difficile toxin (CDT) is a binary actin-ADP-ribosylating toxin that causes depolymerization of the actin cytoskeleton and formation of microtubule-based membrane protrusions, which are suggested to be involved in enhanced bacterial adhesion and colonization of hypervirulent C. difficile...

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Autores principales: Schwan, Carsten, Nölke, Thilo, Kruppke, Anna S., Schubert, Daniel M., Lang, Alexander E., Aktories, Klaus
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190741/
https://ncbi.nlm.nih.gov/pubmed/21705797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.261925
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