Clostridium difficile Toxin CDT Induces Formation of Microtubule-Based Protrusions and Increases Adherence of Bacteria

Clostridium difficile causes antibiotic-associated diarrhea and pseudomembranous colitis by production of the Rho GTPase-glucosylating toxins A and B. Recently emerging hypervirulent Clostridium difficile strains additionally produce the binary ADP-ribosyltransferase toxin CDT (Clostridium difficile...

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Библиографические подробности
Главные авторы: Schwan, Carsten, Stecher, Bärbel, Tzivelekidis, Tina, van Ham, Marco, Rohde, Manfred, Hardt, Wolf-Dietrich, Wehland, Jürgen, Aktories, Klaus
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2009
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757728/
https://ncbi.nlm.nih.gov/pubmed/19834554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000626
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