Raft Protein Clustering Alters N-Ras Membrane Interactions and Activation Pattern

The trafficking, membrane localization, and lipid raft association of Ras proteins, which are crucial oncogenic mediators, dictate their isoform-specific biological responses. Accordingly, their spatiotemporal dynamics are tightly regulated. While extensively studied for H- and K-Ras, such informati...

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Main Authors: Eisenberg, Sharon, Beckett, Alison J., Prior, Ian A., Dekker, Frank J., Hedberg, Christian, Waldmann, Herbert, Ehrlich, Marcelo, Henis, Yoav I.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2011
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187366/
https://ncbi.nlm.nih.gov/pubmed/21807892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05570-11
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