Three Separable Domains Regulate GTP-Dependent Association of H-ras with the Plasma Membrane

The microlocalization of Ras proteins to different microdomains of the plasma membrane is critical for signaling specificity. Here we examine the complex membrane interactions of H-ras with a combination of FRAP on live cells to measure membrane affinity and electron microscopy of intact plasma memb...

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Bibliographische Detailangaben
Hauptverfasser: Rotblat, Barak, Prior, Ian A., Muncke, Cornelia, Parton, Robert G., Kloog, Yoel, Henis, Yoav I., Hancock, John F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC444858/
https://ncbi.nlm.nih.gov/pubmed/15254246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.15.6799-6810.2004
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