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Three Separable Domains Regulate GTP-Dependent Association of H-ras with the Plasma Membrane

The microlocalization of Ras proteins to different microdomains of the plasma membrane is critical for signaling specificity. Here we examine the complex membrane interactions of H-ras with a combination of FRAP on live cells to measure membrane affinity and electron microscopy of intact plasma memb...

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Publicat a:Mol Cell Biol
Autors principals: Rotblat, Barak, Prior, Ian A., Muncke, Cornelia, Parton, Robert G., Kloog, Yoel, Henis, Yoav I., Hancock, John F.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC444858/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15254246/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.15.6799-6810.2004
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