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Raft Protein Clustering Alters N-Ras Membrane Interactions and Activation Pattern
The trafficking, membrane localization, and lipid raft association of Ras proteins, which are crucial oncogenic mediators, dictate their isoform-specific biological responses. Accordingly, their spatiotemporal dynamics are tightly regulated. While extensively studied for H- and K-Ras, such informati...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3187366/ https://ncbi.nlm.nih.gov/pubmed/21807892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05570-11 |
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