Molecular Basis for the Selectivity of Antituberculosis Compounds Capreomycin and Viomycin

Capreomycin and the structurally similar compound viomycin are cyclic peptide antibiotics which are particularly active against Mycobacterium tuberculosis, including multidrug resistant strains. Both antibiotics bind across the ribosomal interface involving 23S rRNA helix 69 (H69) and 16S rRNA helix...

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Detaylı Bibliyografya
Asıl Yazarlar: Akbergenov, Rashid, Shcherbakov, Dmitri, Matt, Tanja, Duscha, Stefan, Meyer, Martin, Wilson, Daniel N., Böttger, Erik C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2011
Konular:
Mechanisms of Action: Physiological Effects
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187005/
https://ncbi.nlm.nih.gov/pubmed/21768509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00628-11
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