The TFIIH subunit Tfb3 regulates cullin neddylation

Cullin proteins are scaffolds for the assembly of multi-subunit ubiquitin ligases, which ubiquitylate a large number of proteins involved in widely-varying cellular functions. Multiple mechanisms cooperate to regulate cullin activity, including neddylation of their C-terminal domain. Interestingly,...

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Main Authors: Rabut, Gwenaël, Le Dez, Gaëlle, Verma, Rati, Makhnevych, Taras, Knebel, Axel, Kurz, Thimo, Boone, Charles, Deshaies, Raymond J., Peter, Matthias
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186349/
https://ncbi.nlm.nih.gov/pubmed/21816351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.05.032
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