Facilitation of Hippocampal Synaptogenesis and Spatial Memory by C-Terminal Truncated Nle(1)-Angiotensin IV Analogs

Angiotensin IV (AngIV; Val(1)-Tyr(2)-Ile(3)-His(4)-Pro(5)-Phe(6))-related peptides have emerged as potential antidementia agents. However, their development as practical therapeutic agents has been impeded by a combination of metabolic instability, poor blood-brain barrier permeability, and an incom...

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Bibliografiske detaljer
Main Authors: Benoist, Caroline C., Wright, John W., Zhu, Mingyan, Appleyard, Suzanne M., Wayman, Gary A., Harding, Joseph W.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2011
Fag:
Behavioral Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186286/
https://ncbi.nlm.nih.gov/pubmed/21719467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.182220
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