Evaluation of Metabolically Stabilized Angiotensin IV Analogs as Procognitive/Antidementia Agents

Angiotensin IV (AngIV: VYIHPF)–related peptides have long been recognized as procognitive agents with potential as antidementia therapeutics. Their development as useful therapeutics, however, has been limited by physiochemical properties that make them susceptible to metabolic degradation and imper...

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Bibliografiske detaljer
Main Authors: McCoy, Alene T., Benoist, Caroline C., Wright, John W., Kawas, Leen H., Bule-Ghogare, Jyote M., Zhu, Mingyan, Appleyard, Suzanne M., Wayman, Gary A., Harding, Joseph W.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2013
Fag:
Drug Discovery and Translational Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533412/
https://ncbi.nlm.nih.gov/pubmed/23055539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.199497
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