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Evaluation of Metabolically Stabilized Angiotensin IV Analogs as Procognitive/Antidementia Agents

Angiotensin IV (AngIV: VYIHPF)–related peptides have long been recognized as procognitive agents with potential as antidementia therapeutics. Their development as useful therapeutics, however, has been limited by physiochemical properties that make them susceptible to metabolic degradation and imper...

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Detalhes bibliográficos
Main Authors: McCoy, Alene T., Benoist, Caroline C., Wright, John W., Kawas, Leen H., Bule-Ghogare, Jyote M., Zhu, Mingyan, Appleyard, Suzanne M., Wayman, Gary A., Harding, Joseph W.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533412/
https://ncbi.nlm.nih.gov/pubmed/23055539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.199497
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