Leptin Induces Hippocampal Synaptogenesis via CREB-Regulated MicroRNA-132 Suppression of p250GAP

Leptin acts in the hippocampus to enhance cognition and reduce depression and anxiety. Cognitive and emotional disorders are associated with abnormal hippocampal dendritic spine formation and synaptogenesis. Although leptin has been shown to induce synaptogenesis in the hypothalamus, its effects on...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dhar, Matasha, Zhu, Mingyan, Impey, Soren, Lambert, Talley J., Bland, Tyler, Karatsoreos, Ilia N., Nakazawa, Takanobu, Appleyard, Suzanne M., Wayman, Gary A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Endocrine Society 2014
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075163/
https://ncbi.nlm.nih.gov/pubmed/24877561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1332
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