The Environmental Neurotoxicant PCB 95 Promotes Synaptogenesis via Ryanodine Receptor-Dependent miR132 Upregulation

Non–dioxin-like (NDL) polychlorinated biphenyls (PCBs) are widespread environmental contaminants linked to neuropsychological dysfunction in children. NDL PCBs increase spontaneous Ca(2+) oscillations in neurons by stabilizing ryanodine receptor (RyR) calcium release channels in the open configurati...

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Main Authors: Lesiak, Adam, Zhu, Mingyan, Chen, Hao, Appleyard, Suzanne M., Impey, Soren, Lein, Pamela J., Wayman, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2014
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891953/
https://ncbi.nlm.nih.gov/pubmed/24431430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2884-13.2014
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