HIV-1 Integrase-DNA Recognition Mechanisms

Integration of a reverse transcribed DNA copy of the HIV viral genome into the host chromosome is essential for virus replication. This process is catalyzed by the virally encoded protein integrase. The catalytic activities, which involve DNA cutting and joining steps, have been recapitulated in vit...

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Bibliografiske detaljer
Main Authors: Kessl, Jacques J., McKee, Christopher J., Eidahl, Jocelyn O., Shkriabai, Nikolozi, Katz, Ari, Kvaratskhelia, Mamuka
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Diversity Preservation International (MDPI) 2009
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185514/
https://ncbi.nlm.nih.gov/pubmed/21994566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v1030713
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