Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53

Activation of p53 by DNA damage results in either cell cycle arrest, allowing DNA repair and cell survival, or induction of apoptosis. As these opposite outcomes are both mediated by p53 stabilization, additional mechanisms to determine this decision must exist. Here we show that glycogen synthase k...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Charvet, Céline, Wissler, Manuela, Brauns-Schubert, Prisca, Wang, Shang-Jui, Tang, Yi, Sigloch, Florian C., Mellert, Hestia, Brandenburg, Martin, Lindner, Silke E., Breit, Bernhard, Green, Douglas R., McMahon, Steven B., Borner, Christoph, Gu, Wei, Maurer, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184637/
https://ncbi.nlm.nih.gov/pubmed/21658600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.03.033
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados