CDK9‐mediated phosphorylation controls the interaction of TIP60 with the transcriptional machinery

The acetyltransferase TIP60 is regulated by phosphorylation, and we have previously shown that phosphorylation of TIP60 on S86 by GSK‐3 promotes p53‐mediated induction of the BCL‐2 protein PUMA. TIP60 phosphorylation by GSK‐3 requires a priming phosphorylation on S90, and here, we identify CDK9 as a...

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Detaylı Bibliyografya
Yayımlandı:EMBO Rep
Asıl Yazarlar: Brauns‐Schubert, Prisca, Schubert, Florian, Wissler, Manuela, Weiss, Martina, Schlicher, Lisa, Bessler, Simon, Safavi, Mariam, Miething, Cornelius, Borner, Christoph, Brummer, Tilman, Maurer, Ulrich
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Scientific Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797957/
https://ncbi.nlm.nih.gov/pubmed/29335245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744311
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