SPATA2 promotes CYLD activity and regulates TNF‐induced NF‐κB signaling and cell death

K63‐ and Met1‐linked ubiquitylation are crucial posttranslational modifications for TNF receptor signaling. These non‐degradative ubiquitylations are counteracted by deubiquitinases (DUBs), such as the enzyme CYLD, resulting in an appropriate signal strength, but the regulation of this process remai...

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Pubblicato in:EMBO Rep
Autori principali: Schlicher, Lisa, Wissler, Manuela, Preiss, Florian, Brauns‐Schubert, Prisca, Jakob, Celia, Dumit, Veronica, Borner, Christoph, Dengjel, Joern, Maurer, Ulrich
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048381/
https://ncbi.nlm.nih.gov/pubmed/27458237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642592
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