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SPATA2 promotes CYLD activity and regulates TNF‐induced NF‐κB signaling and cell death
K63‐ and Met1‐linked ubiquitylation are crucial posttranslational modifications for TNF receptor signaling. These non‐degradative ubiquitylations are counteracted by deubiquitinases (DUBs), such as the enzyme CYLD, resulting in an appropriate signal strength, but the regulation of this process remai...
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| Publicado no: | EMBO Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5048381/ https://ncbi.nlm.nih.gov/pubmed/27458237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642592 |
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