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High-Throughput Screen for Identifying Small Molecules That Target Fungal Zinc Homeostasis

Resistance to traditional antifungal drugs has increased significantly over the past three decades, making identification of novel antifungal agents and new targets an emerging priority. Based on the extraordinary zinc requirement of several fungal pathogens and their well-established sensitivity to...

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Autori principali: Simm, Claudia, Luan, Chi-Hao, Weiss, Eric, O'Halloran, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182986/
https://ncbi.nlm.nih.gov/pubmed/21980385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025136
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