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High-Throughput Screen for Identifying Small Molecules That Target Fungal Zinc Homeostasis

Resistance to traditional antifungal drugs has increased significantly over the past three decades, making identification of novel antifungal agents and new targets an emerging priority. Based on the extraordinary zinc requirement of several fungal pathogens and their well-established sensitivity to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Simm, Claudia, Luan, Chi-Hao, Weiss, Eric, O'Halloran, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182986/
https://ncbi.nlm.nih.gov/pubmed/21980385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025136
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