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High-Throughput Screen for Identifying Small Molecules That Target Fungal Zinc Homeostasis

Resistance to traditional antifungal drugs has increased significantly over the past three decades, making identification of novel antifungal agents and new targets an emerging priority. Based on the extraordinary zinc requirement of several fungal pathogens and their well-established sensitivity to...

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Библиографические подробности
Главные авторы: Simm, Claudia, Luan, Chi-Hao, Weiss, Eric, O'Halloran, Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182986/
https://ncbi.nlm.nih.gov/pubmed/21980385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025136
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