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Structure and dynamics of a conformationally constrained nitroxide side chain and applications in EPR spectroscopy
A disulfide-linked nitroxide side chain (R1) is the most widely used spin label for determining protein topology, mapping structural changes, and characterizing nanosecond backbone motions by site-directed spin labeling. Although the internal motion of R1 and the number of preferred rotamers are lim...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3182725/ https://ncbi.nlm.nih.gov/pubmed/21911399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111420108 |
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