A rigid disulfide-linked nitroxide side chain simplifies the quantitative analysis of PRE data

The measurement of (1)H transverse paramagnetic relaxation enhancement (PRE) has been used in biomolecular systems to determine long-range distance restraints and to visualize sparsely-populated transient states. The intrinsic flexibility of most nitroxide and metal-chelating paramagnetic spin-label...

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Main Authors: Fawzi, Nicolas L., Fleissner, Mark R., Anthis, Nicholas J., Kálai, Tamás, Hideg, Kálmán, Hubbell, Wayne L., Clore, G. Marius
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489005/
https://ncbi.nlm.nih.gov/pubmed/21947919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-011-9545-x
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