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Conformational analysis of a nitroxide side chain in α-helices with Density Functional Theory

In site directed spin labeling, a nitroxide side chain is introduced at a selected site in a protein; the most commonly used is a disulfide-linked side chain designated R1. The EPR spectra of R1, and the interspin distance between pairs of R1 residues as determined by dipolar EPR spectroscopy, encod...

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Detalhes bibliográficos
Main Authors: Warshaviak, Dora Toledo, Serbulea, Laura, Houk, K. N., Hubbell, Wayne L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267783/
https://ncbi.nlm.nih.gov/pubmed/21162593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp108871m
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