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Resolving Conformational and Rotameric Exchange in Spin-Labeled Proteins Using Saturation Recovery EPR

The function of many proteins involves equilibria between conformational substates, and to elucidate mechanisms of function it is essential to have experimental tools to detect the presence of conformational substates and to determine the time scale of exchange between them. Site-directed spin label...

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Auteurs principaux: Bridges, Michael D., Hideg, Kálmán, Hubbell, Wayne L.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821067/
https://ncbi.nlm.nih.gov/pubmed/20157634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00723-009-0079-2
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