Metabolic Regulation of Protein N-alpha-acetylation by Bcl-xL Promotes Cell Survival

Previous experiments suggest a connection between the N-alpha-acetylation of proteins and the sensitivity of cells to apoptotic signals. Here, we describe a novel biochemical assay to detect the acetylation status of proteins and demonstrate that protein N-alpha-acetylation is regulated by the avail...

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Detalhes bibliográficos
Main Authors: Yi, Caroline H., Pan, Heling, Seebacher, Jan, Jang, Il-Ho, Hyberts, Sven G., Heffron, Gregory J., Vander Heiden, Matthew G., Yang, Renliang, Li, Fupeng, Locasale, Jason W., Sharfi, Hadar, Zhai, Bo, Rodriguez-Mias, Ricard, Luithardt, Harry, Cantley, Lewis C., Daley, George Q., Asara, John M., Gygi, Steven P., Wagner, Gerhard, Liu, Chuan-Fa, Yuan, Junying
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182480/
https://ncbi.nlm.nih.gov/pubmed/21854985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.06.050
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