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Prognostic significance of Bcl-xL expression and efficacy of Bcl-xL targeting therapy in urothelial carcinoma

BACKGROUND: Bcl-xL has an important role in the control of cell death through its inhibition of apoptosis. The aim of this study was to investigate the clinicopathological significance of Bcl-xL in upper urinary tract urothelial carcinoma (UTUC) and the therapeutic effect of targeting Bcl-xL protein...

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Autores principales: Yoshimine, S, Kikuchi, E, Kosaka, T, Mikami, S, Miyajima, A, Okada, Y, Oya, M
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681018/
https://ncbi.nlm.nih.gov/pubmed/23674090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.216
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