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Bcl-xL Inhibitor ABT-737 Reveals a Dual Role for Bcl-xL in Synaptic Transmission

A role for BCL-xL in regulating neuronal activity is suggested by its dramatic effects on synaptic function and mitochondrial channel activity. When recombinant BCL-xL is injected into the giant presynaptic terminal of squid stellate ganglion or applied directly to mitochondrial outer membranes with...

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Detalhes bibliográficos
Main Authors: Hickman, John A., Hardwick, J. Marie, Kaczmarek, Leonard K., Jonas, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836590/
https://ncbi.nlm.nih.gov/pubmed/18160428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00598.2007
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