Synergistic Silencing: Combinations of Lipid-like Materials for Efficacious siRNA Delivery

Despite the promise of RNA interference (RNAi) therapeutics, progress toward the clinic has been slowed by the difficulty of delivering short interfering RNA (siRNA) into cellular targets within the body. Nearly all siRNA delivery vehicles developed to date employ a single cationic or ionizable mate...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Whitehead, Kathryn A, Sahay, Gaurav, Li, George Z, Love, Kevin T, Alabi, Christopher A, Ma, Minglin, Zurenko, Christopher, Querbes, William, Langer, Robert S, Anderson, Daniel G
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2011
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182356/
https://ncbi.nlm.nih.gov/pubmed/21750531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.141
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