Inhibitory effects of the JAK inhibitor CP690,550 on human CD4(+ )T lymphocyte cytokine production

BACKGROUND: The new JAK3 inhibitor, CP690,550, has shown efficacy in the treatment of rheumatoid arthritis. The present study was undertaken to assess the effects of CP690,550 on cytokine production and cellular signaling in human CD4(+ )T cells. RESULTS: CD4(+ )T cells produced IL-2, IL-4, IL-17, I...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Migita, Kiyoshi, Miyashita, Taiichiro, Izumi, Yasumori, Koga, Tomohiro, Komori, Atsumasa, Maeda, Yumi, Jiuchi, Yuka, Aiba, Yoshihiro, Yamasaki, Satoshi, Kawakami, Atsushi, Nakamura, Minoru, Ishibashi, Hiromi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2011
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179939/
https://ncbi.nlm.nih.gov/pubmed/21884580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-12-51
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