Characterization of the Rac guanine nucleotide exchange factor P-Rex1 in platelets

BACKGROUND: Blood platelets undergo a carefully regulated change in shape to serve as the primary mediators of hemostasis and thrombosis. These processes manifest through platelet spreading and aggregation and are dependent on platelet actin cytoskeletal changes orchestrated by the Rho GTPase family...

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Main Authors: Aslan, Joseph E, Spencer, Alex M, Loren, Cassandra P, Pang, Jiaqing, Welch, Heidi C, Greenberg, Daniel L, McCarty, Owen JT
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
主題:
Short Report
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179747/
https://ncbi.nlm.nih.gov/pubmed/21884615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-6-11
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