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Role for the guanine nucleotide exchange factor P-Rex1 in platelet secretion and aggregation
OBJECTIVE: Recent studies have shown a role for Rac1 in regulating platelet functions, but how Rac1 is activated in platelets remains unclear. PIP3-dependent Rac exchanger 1 (P-Rex1) was originally identified in neutrophils that regulates phagocyte functions. We sought to examine whether P-Rex1 play...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288658/ https://ncbi.nlm.nih.gov/pubmed/22207728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.243675 |
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