Characterization of the Rac guanine nucleotide exchange factor P-Rex1 in platelets

BACKGROUND: Blood platelets undergo a carefully regulated change in shape to serve as the primary mediators of hemostasis and thrombosis. These processes manifest through platelet spreading and aggregation and are dependent on platelet actin cytoskeletal changes orchestrated by the Rho GTPase family...

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Bibliographic Details
Main Authors: Aslan, Joseph E, Spencer, Alex M, Loren, Cassandra P, Pang, Jiaqing, Welch, Heidi C, Greenberg, Daniel L, McCarty, Owen JT
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Short Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179747/
https://ncbi.nlm.nih.gov/pubmed/21884615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-6-11
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