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Characterization of the Rac guanine nucleotide exchange factor P-Rex1 in platelets

BACKGROUND: Blood platelets undergo a carefully regulated change in shape to serve as the primary mediators of hemostasis and thrombosis. These processes manifest through platelet spreading and aggregation and are dependent on platelet actin cytoskeletal changes orchestrated by the Rho GTPase family...

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Bibliografiske detaljer
Main Authors: Aslan, Joseph E, Spencer, Alex M, Loren, Cassandra P, Pang, Jiaqing, Welch, Heidi C, Greenberg, Daniel L, McCarty, Owen JT
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179747/
https://ncbi.nlm.nih.gov/pubmed/21884615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-6-11
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