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S6K1 and mTOR regulate Rac1-driven platelet activation and aggregation

Platelet activation and thrombus formation are under the control of signaling systems that integrate cellular homeostasis with cytoskeletal dynamics. Here, we identify a role for the ribosome protein S6 kinase (S6K1) and its upstream regulator mTOR in the control of platelet activation and aggregate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Aslan, Joseph E., Tormoen, Garth W., Loren, Cassandra P., Pang, Jiaqing, McCarty, Owen J. T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175787/
https://ncbi.nlm.nih.gov/pubmed/21757621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-02-331579
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