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PAK signaling coordinates GPVI-mediated platelet aggregation, lamellipodia formation and aggregate stability under shear
OBJECTIVE: Rho GTPase proteins play a central role in regulating the dynamics of the platelet actin cytoskeleton. Yet, little is known regarding how Rho GTPase activation coordinates platelet activation and function. In this study, we aimed to characterize the role of the Rho GTPase effector p21 act...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3938029/ https://ncbi.nlm.nih.gov/pubmed/23640496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.301165 |
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