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Characterization of the Rac guanine nucleotide exchange factor P-Rex1 in platelets

BACKGROUND: Blood platelets undergo a carefully regulated change in shape to serve as the primary mediators of hemostasis and thrombosis. These processes manifest through platelet spreading and aggregation and are dependent on platelet actin cytoskeletal changes orchestrated by the Rho GTPase family...

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Библиографические подробности
Главные авторы: Aslan, Joseph E, Spencer, Alex M, Loren, Cassandra P, Pang, Jiaqing, Welch, Heidi C, Greenberg, Daniel L, McCarty, Owen JT
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179747/
https://ncbi.nlm.nih.gov/pubmed/21884615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-6-11
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