Characterization of Dibenzo[a,l ]pyrene-trans-11,12-diol (Dibenzo[def,p]chrysene) Glucuronidation by UDP-glucuronosyltransferases

Dibenzo[a,l]pyrene (DB[a,l]P) (dibenzo[def,p]chrysene) is a highly carcinogenic polycyclic aromatic hydrocarbon (PAH) that has been identified in tobacco smoke and is found in our environment due to incomplete combustion of organic matter. Its metabolites are known to form stable DNA adducts in bact...

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Autores principales: Olson, Kristine C., Sun, Dongxiao, Chen, Gang, Sharma, Arun K., Amin, Shantu, Ropson, Ira J., Spratt, Thomas E., Lazarus, Philip
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177992/
https://ncbi.nlm.nih.gov/pubmed/21780761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200178v
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