PRELIMINARY PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS FOR BENZO[A]PYRENE AND DIBENZO[DEF, P]CHRYSENE IN RODENTS

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants generated as byproducts of natural and anthropogenic combustion processes. Despite significant public health concern, physiologically based pharmacokinetic (PBPK) modeling efforts for PAHs have so far been limited to n...

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Главные авторы: Crowell, Susan Ritger, Amin, Shantu G., Anderson, Kim A., Krishnegowda, Gowdahalli, Sharma, Arun K., Soelberg, Jolen J., Williams, David E., Corley, Richard A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226888/
https://ncbi.nlm.nih.gov/pubmed/22001385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2011.09.020
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