PRELIMINARY PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS FOR BENZO[A]PYRENE AND DIBENZO[DEF, P]CHRYSENE IN RODENTS

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants generated as byproducts of natural and anthropogenic combustion processes. Despite significant public health concern, physiologically based pharmacokinetic (PBPK) modeling efforts for PAHs have so far been limited to n...

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Bibliografiske detaljer
Main Authors: Crowell, Susan Ritger, Amin, Shantu G., Anderson, Kim A., Krishnegowda, Gowdahalli, Sharma, Arun K., Soelberg, Jolen J., Williams, David E., Corley, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226888/
https://ncbi.nlm.nih.gov/pubmed/22001385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2011.09.020
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