PRELIMINARY PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS FOR BENZO[A]PYRENE AND DIBENZO[DEF, P]CHRYSENE IN RODENTS

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants generated as byproducts of natural and anthropogenic combustion processes. Despite significant public health concern, physiologically based pharmacokinetic (PBPK) modeling efforts for PAHs have so far been limited to n...

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Detalhes bibliográficos
Main Authors: Crowell, Susan Ritger, Amin, Shantu G., Anderson, Kim A., Krishnegowda, Gowdahalli, Sharma, Arun K., Soelberg, Jolen J., Williams, David E., Corley, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226888/
https://ncbi.nlm.nih.gov/pubmed/22001385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2011.09.020
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