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Characterization of Dibenzo[a,l ]pyrene-trans-11,12-diol (Dibenzo[def,p]chrysene) Glucuronidation by UDP-glucuronosyltransferases

Dibenzo[a,l]pyrene (DB[a,l]P) (dibenzo[def,p]chrysene) is a highly carcinogenic polycyclic aromatic hydrocarbon (PAH) that has been identified in tobacco smoke and is found in our environment due to incomplete combustion of organic matter. Its metabolites are known to form stable DNA adducts in bact...

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Detalhes bibliográficos
Main Authors: Olson, Kristine C., Sun, Dongxiao, Chen, Gang, Sharma, Arun K., Amin, Shantu, Ropson, Ira J., Spratt, Thomas E., Lazarus, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177992/
https://ncbi.nlm.nih.gov/pubmed/21780761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200178v
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