Characterization of Dibenzo[a,l ]pyrene-trans-11,12-diol (Dibenzo[def,p]chrysene) Glucuronidation by UDP-glucuronosyltransferases

Dibenzo[a,l]pyrene (DB[a,l]P) (dibenzo[def,p]chrysene) is a highly carcinogenic polycyclic aromatic hydrocarbon (PAH) that has been identified in tobacco smoke and is found in our environment due to incomplete combustion of organic matter. Its metabolites are known to form stable DNA adducts in bact...

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Hlavní autoři: Olson, Kristine C., Sun, Dongxiao, Chen, Gang, Sharma, Arun K., Amin, Shantu, Ropson, Ira J., Spratt, Thomas E., Lazarus, Philip
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177992/
https://ncbi.nlm.nih.gov/pubmed/21780761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200178v
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