A carregar...

Structural study of phenyl boronic acid derivatives as AmpC β-lactamase inhibitors

A small set of boronic acids acting as low nanomolar inhibitors of AmpC β-lactamase were designed and synthesized in the effort to improve affinity, pharmacokinetic properties, and to provide a valid lead compound. X-ray crystallography revealed the binary complex of the best inhibitor bound to the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tondi, Donatella, Calò, Samuele, Shoichet, Brian K., Costi, Maria Paola
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177945/
https://ncbi.nlm.nih.gov/pubmed/20452208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.04.007
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!