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X-ray Crystallography Deciphers the Activity of Broad-Spectrum Boronic Acid β-Lactamase Inhibitors

[Image: see text] Recent decades have witnessed a dramatic increase of multidrug resistant (MDR) bacteria, compromising the efficacy of available antibiotics, and a continual decline in the discovery of novel antibacterials. We recently reported the first library of benzo[b]thiophen-2-ylboronic acid...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Cendron, Laura, Quotadamo, Antonio, Maso, Lorenzo, Bellio, Pierangelo, Montanari, Martina, Celenza, Giuseppe, Venturelli, Alberto, Costi, Maria Paola, Tondi, Donatella
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466825/
https://ncbi.nlm.nih.gov/pubmed/30996812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00607
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