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Targeting the Class A Carbapenemase GES-5 via Virtual Screening

The worldwide spread of β-lactamases able to hydrolyze last resort carbapenems contributes to the antibiotic resistance problem and menaces the successful antimicrobial treatment of clinically relevant pathogens. Class A carbapenemases include members of the KPC and GES families. While drugs against...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Klein, Raphael, Cendron, Laura, Montanari, Martina, Bellio, Pierangelo, Celenza, Giuseppe, Maso, Lorenzo, Tondi, Donatella, Brenk, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072645/
https://ncbi.nlm.nih.gov/pubmed/32075131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10020304
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