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Abnormal Tau, Mitochondrial Dysfunction, Impaired Axonal Transport of Mitochondria, and Synaptic Deprivation in Alzheimer’s Disease
Growing evidence suggests that amyloid beta (Aβ) and tau pathologies are strongly associated with mitochondrial dysfunction and neuronal damage in Alzheimer’s disease (AD). Extensive research of AD postmortem brains, mouse and fly models, including triple transgenic AD mice and mutant tau mice, and...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3176990/ https://ncbi.nlm.nih.gov/pubmed/21872849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2011.07.052 |
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