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Comparison of Ocular Pathologies in Vitamin A–Deficient Mice and RPE65 Gene Knockout Mice

PURPOSE. RPE65 gene knockout (Rpe65(−/−)) mice showed abolished isomerohydrolase activity in the visual cycle and were considered a model for vitamin A deficiency in the retina. The purpose of this study was to compare the retinal phenotypes between vitamin A–deficient (VAD) mice and Rpe65(−/−) mice...

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Detalhes bibliográficos
Main Authors: Hu, Yang, Chen, Ying, Moiseyev, Gennadiy, Takahashi, Yusuke, Mott, Robert, Ma, Jian-xing
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176065/
https://ncbi.nlm.nih.gov/pubmed/21551411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-7118
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