RPE65 from Cone-dominant Chicken Is a More Efficient Isomerohydrolase Compared with That from Rod-dominant Species

Cones recover their photosensitivity faster than rods after bleaching. It has been suggested that a higher rate regeneration of 11-cis-retinal, the chromophore for visual pigments, is required for cones to continuously function under bright light conditions. RPE65 is the isomerohydrolase catalyzing...

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Bibliographic Details
Main Authors: Moiseyev, Gennadiy, Takahashi, Yusuke, Chen, Ying, Kim, Seoyoung, Ma, Jian-xing
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Enzyme Catalysis and Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276383/
https://ncbi.nlm.nih.gov/pubmed/18216020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M703654200
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