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RPE65 is the isomerohydrolase in the retinoid visual cycle

RPE65 is an abundant protein in the retinal pigment epithelium. Mutations in RPE65 are associated with inherited retinal dystrophies. Although it is known that RPE65 is critical for regeneration of 11-cis retinol in the visual cycle, the function of RPE65 is elusive. Here we show that recombinant RP...

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Main Authors: Moiseyev, Gennadiy, Chen, Ying, Takahashi, Yusuke, Wu, Bill X., Ma, Jian-xing
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1194921/
https://ncbi.nlm.nih.gov/pubmed/16116091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503460102
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