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Mechanisms of trinucleotide repeat instability during human development
Trinucleotide expansion underlies several human diseases. Expansion occurs during multiple stages of human development in different cell types, and is sensitive to the gender of the parent who transmits the repeats. Repair and replication models for expansions have been described, but we do not know...
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3175376/ https://ncbi.nlm.nih.gov/pubmed/20953213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg2828 |
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