tPA regulates pulmonary vascular activity through NMDA receptors

Tissue-type plasminogen activator (tPA) is a potent fibrinolytic enzyme used to treat acute coronary artery obstruction. However, tPA has shown limited utility in other disorders caused by thrombotic vascular occlusion, such as pulmonary embolism. We found that tPA caused dose-dependent effects on t...

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Detalhes bibliográficos
Main Authors: Nassar, Taher, Bdeir, Khalil, Yarovoi, Serge, Fanne, Rami Abu, Murciano, Juan-Carlos, Idell, Steven, Allen, Timothy Craig, Cines, Douglas B., Higazi, Abd Al-Roof
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174743/
https://ncbi.nlm.nih.gov/pubmed/21571905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00429.2010
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