Urokinase Plasminogen Activator Regulates Pulmonary Arterial Contractility and Vascular Permeability in Mice

The concentration of urokinase plasminogen activator (uPA) is elevated in pathological settings such as acute lung injury, where pulmonary arterial contractility and permeability are disrupted. uPA limits the accretion of fibrin after injury. Here we investigated whether uPA also regulates pulmonary...

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Autores principales: Nassar, Taher, Yarovoi, Serge, Fanne, Rami Abu, Waked, Otailah, Allen, Timothy C., Idell, Steven, Cines, Douglas B., Higazi, Abd Al-Roof
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2011
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262683/
https://ncbi.nlm.nih.gov/pubmed/21617202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0302OC
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