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Urokinase Plasminogen Activator Regulates Pulmonary Arterial Contractility and Vascular Permeability in Mice

The concentration of urokinase plasminogen activator (uPA) is elevated in pathological settings such as acute lung injury, where pulmonary arterial contractility and permeability are disrupted. uPA limits the accretion of fibrin after injury. Here we investigated whether uPA also regulates pulmonary...

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Detalhes bibliográficos
Main Authors: Nassar, Taher, Yarovoi, Serge, Fanne, Rami Abu, Waked, Otailah, Allen, Timothy C., Idell, Steven, Cines, Douglas B., Higazi, Abd Al-Roof
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262683/
https://ncbi.nlm.nih.gov/pubmed/21617202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0302OC
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